- Methylation Aid: Features body-ready folate and vitamin B12 to aid in methylation, a vital process for maintaining cellular health and function*
- SAMe Content: Metagenics Blisphora provides 400 mg of S-adenosyl-L-methionine (SAMe) to support metabolic processes*
- Non-GMO & Gluten-Free: Take one vegetarian tablet daily 30 minutes before a meal on an empty stomach with water or as directed by your healthcare practitioner
- Designed by Nature, Trusted by Doctors: At Metagenics, we connect people with products that help them live healthier, happier lives
- As the #1 Doctor Recommended Professional Supplement Brand, Metagenics delivers clinically proven, precision-crafted formulas to support your health at its core—because true wellness starts with integrity, balance, and expertise


MC –
I love love love this product
I love love love this product, i instantly feel my mood lifted after i take them
RobertaL –
… the products I’ve bought from Metagenics seem to be good quality products and work well
All of the products I’ve bought from Metagenics seem to be good quality products and work well.
M5 –
Great product, but way super expensive to sustain
These work awesomely, but they are super expensive – especially if you take 400mg a day, or 800mg a day, you’re talking 2-4 tablets a day, and there are only 30 in the box. Super expensive so 4 stars. I found a much cheaper brand (~$35 for 60) and then take them with a b-complex – works as well as these.
Rachel D Neuberger –
Five Stars
great product
shiny_eel2153 –
Great supplement for health and I take it daily
Have been using it for a year now and it helps me with my mood and sleep.
More_Than_A_Review –
worth it
worth the money
JRenee –
Worth it!
So helpful for mood & sleep. Noticeable decrease in joint pain, as well. I have tried less extensive brands but not as effective as Metagenics. My happy pill.