- ADVANCED NAD+ SUPPORT – Delivers 500 mg of nicotinamide riboside (NR) plus 250 mg of TMG to boost NAD+ production and help sustain NAD+ pathways.
- BOOSTS CELLULAR ENERGY – NR, a vitamin B3 derivative and NAD+ precursor, supports ATP energy production and promotes optimal mitochondrial function for healthy aging.
- PROMOTES HEALTHY METHYLATION – TMG is a key methyl donor that supports balanced homocysteine and helps sustain NAD+ pathways. A smart addition when taking NR to help maintain methyl reserves.
- DOCTOR-FORMULATED FOR EVERYDAY USE – Created by longevity experts, this powerful formula supports healthy aging and energy maintenance. We recommend taking 2 capsules each morning to support and sustain healthy NAD+ levels.
- QUALITY YOU CAN TRUST SINCE 1988 – Proudly manufactured in the USA and triple-tested for purity and potency. Every batch is verified by independent third-party labs, with full results published online for complete transparency and your peace of mind.
- THIS HOLIDAY SEASON, GIVE THE GIFT OF HEALTH – ProHealth’s science-backed supplements make a meaningful Christmas present for loved ones focused on longevity, energy, and well-being.
8 avaliações para ProHealth Nicotinamide Riboside Pro 500 | 60 Capsules | 500 mg NR + 250 mg TMG | NAD+ Precursor for Cellular Energy, Mitochondrial Support & Healthy Aging | USA Manufactured, Triple Lab-Tested
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Val Lipow –
Product Review
Product is helping with my word retrieval memory.
Luisa Martínez –
Un buen producto
Compré este producto porque me lo recomendó La IA y me pareció bueno luego de revisarlo lo he comprado una vez y la relación precio calidad es buena. Ahora se me acabó pero estoy probando con otro este es bastante bueno tal vez lo vuelva a comprar si el que estoy probando, ahora no es mejor
Torres –
Must buy
Absolutely love this product. I was taking this along with NMN. Would definitely recommend.
Cliente de Amazon –
Buen producto
Muy buen producto 👍🏻
kLr –
Brand quality and transparency offering another of many NAD+ boosting formulas
Another NAD+ booster from a reputable brand. I have used NAD boosters for some time, as a 59 year old woman looking to optimize health and the challenges that come with aging. With high cholesterol, lagging energy and aging skin being my biggest reasons for incorporating more B3 into my stack, I’ve tried several forms, from niacin to niacinamide, to NMN. They all have different pathways in the body, but ultimately my goal is to raise my blood NAD+ levels.Serving size is 2 capsules, so this will last a month at that recommendation.Apparently the pathway for NR is to convert to NMN and then to NAD.This supplement is not just NR, it contains TMG (recommended when taking high B3 for methylation — I take a separate TMG capsule when taking niacinamide). It’s nice to have both in one formula. It also contains the NIAGEN form of NR which is a well-studied branded NR variant.I take a lot of supplements and they can add up, so it’s important to me that they are not just effective, but a good value proposition and safe. ProHealth Longevity — a company in business since 1988 — has a solid track record for quality control and transparency.Prohealth’s “TrustScore” is listed as High with a 7.87 out of 10 rating as of June 2026This product is listed as Good with a 7.94 out of 10 rating.It is confirmed made at a cGMP 3rd party certified facility.It is 3rd party lab tested as ISO accredited testing labs for purity, identity, potency and heavy metals. Lot tested, with public batch specific certificates of analysisAll of the inactive ingredients are considered safe.Lot # and “Best By” date is printed on the bottle.It’s hard to quantify changes in the short term on an individual basis, especially with this type of supplement which I consider to be a long-term health optimizer. So many factors come into play in how I may feel on a particular day that it’s hard to pinpoint why I may feel extra energized or more sluggish (did I sleep well, am I stressed about something, did I drink alcohol the day before, how well am I eating, etc). I am very interested in getting the resources my body needs to have the best outcome it can have, along with lifestyle and dietary habits. Based on the above information about the company I have a lot of confidence in the safety and purity of this supplement, and based on the current science on NAD boosters, I view this as a great tool toward that goal.
Amazon Customer –
Thoughtfully Formulated NR and TMG Supplement With Excellent Quality Transparency
At 39, I’ve become much more intentional about taking care of myself and paying attention to what I put into my body. I’ve gradually built a more thoughtful supplement routine, and this ProHealth Nicotinamide Riboside Pro 500 interested me as another option for supporting my overall wellness as I get older.The formula is refreshingly focused. A full two-capsule serving provides 500 mg of nicotinamide riboside, or NR, along with 250 mg of TMG. I especially appreciate having both ingredients together rather than needing to purchase and keep track of two separate supplements. It’s also important to note that the 500 mg amount is for the complete two-capsule serving, not each individual capsule. This gives me the option of taking the full suggested serving or starting with one capsule when I want a more gradual addition to my routine.The capsules are a manageable, average size and easy for me to incorporate with the rest of my daily supplements. They don’t have an unpleasant smell or taste, which matters when something is intended for consistent use. I also like that the formula is simple rather than being crowded with a long list of extra ingredients that may overlap with products I already take.One of the most reassuring aspects is ProHealth’s attention to quality documentation. The bottle arrived securely sealed, with clear serving information, a lot number, and an expiration date. The company also provides batch-testing information, which gives me more confidence than a vague quality statement without any supporting transparency. With a supplement in this price range, I want to know that care has gone into verifying what is actually inside.This is a 60-capsule bottle, so it provides approximately 30 full servings when taken as directed. It is a premium monthly supplement, but the straightforward formula, inclusion of TMG, established brand, and testing transparency help explain the cost. I also appreciate that it isn’t positioned like a stimulant. I’m not expecting an instant rush of energy or an overnight transformation. For me, this is the type of supplement that makes the most sense as part of a consistent, long-term wellness routine, with realistic expectations about what can and cannot be personally measured.Overall, this feels like a polished, carefully presented option for someone specifically interested in adding NR and TMG to an established supplement routine. The clear dosing, easy capsules, focused ingredient list, and emphasis on testing are exactly the qualities I look for when deciding whether a supplement deserves a regular place in my day.
Doug M.Doug M. –
Supports Longevity and Healthy Aging by Supplementing Declining NAD+ LevelsSupports Longevity and Healthy Aging by Supplementing Declining NAD+ Levels
Nicotinamide riboside hydrogen malate (NRHM), the form used in the ProHealth Pro 500 supplement, is a combination of nicotinamide riboside, a form of vitamin B3, and hydrogen malate, which is thought to enhance the stability and absorption of nicotinamide riboside. Nicotinamide riboside is a naturally occurring molecule and a precursor to nicotinamide adenine dinucleotide (NAD+); it’s a smaller molecule that the body converts into NAD+ through a series of metabolic processes. NAD+ is involved in various important biological processes that include metabolism, cell signaling, gene regulation, DNA repair and the regulation of aging-related pathways. ProHealth’s “New Formula” of NRHM includes Trimethylglycine (TMG) which helps to lower homocysteine levels, enhances cellular hydration, and may increase exercise performance. It also plays an important role in methylation, which is important for gene expression and overall cellular function. HRHM and TMG work synergistically to support cellular health.NAD+ levels decline significantly as we age, typically starting at around age 30 and potentially dropping by up to 50% by age 40, consequently impairing cellular functions that can contribute to age-related dysfunction and disease, in effect, driving the aging process. This steep decline is due in part because the body produces less of it, but also because as we age, more is needed to combat age-related cell damage and inflammation. Studies have shown that maintaining or increasing healthy levels of NAD+ can sustain and improve health. Moreover, supporting healthy NAD+ levels has the benefits of combating age related memory loss, increasing physical strength and endurance as well as promoting a longer, healthier life in general.The body does not naturally produce NAD+ but metabolizes it through the use of precursors like nicotinamide riboside. Dietary sources that supply NAD+ precursors such as niacin and tryptophan include animal protein, particularly poultry and fish, legumes, grains, and dairy products. Foods rich in niacin and tryptophan are particularly effective in supporting NAD+ production. Additional sources are liver, tuna, turkey, chicken breast, peanuts, mushrooms, eggs, milk, and cheese. A diet lacking niacin and tryptophan rich foods would likely benefit from ProHealth’s Nicotinamide Riboside supplement, especially those over age 40.ProHealth Longevity is a 38-year-old American company that specializes in a science and physician-based approach to the development of products aimed at maintaining health and vitality while aging and increased longevity. They state that all of their products are manufactured in FDA and GMP facilities and that every batch is third-party tested for quality, purity and potency, often multiple times during the manufacturing process. It’s further stated on their website that their products are manufactured and lab tested in the United States. To back up their statements, they provide a Certificate of Analysis for each of their nutraceuticals and supplements; it’s even possible to chat with a “longevity expert” directly from their website. For those interested, the ProHealth Longevity website includes a “Learn” section with fascinating information about the science behind their supplements. Most importantly, they specialize in targeting and ameliorating the biological systems that slow with age. In fact, I’ve ordered a number of products from ProHealth because I consider them a trusted seller; they are as transparent as any seller I’ve come across.ProHealth recommends a dosage of two capsules daily with or without food, which supplies 500mg of NRHM, a fairly substantial dose in my experience, although there are no serious side effects associated with nicotinamide riboside within the scope of normal usage. Nonetheless, for those that are new to the use of nicotinamide riboside or have a diet rich in the foods mentioned earlier, a one tablet dose supplying 250mg of NRHM may be all that’s needed.
SACSAC –
works for me, even better than NMNworks for me, even better than NMN
I have chronic energy issues due to a post-viral condition. I stumbled onto NAD pathway supplementation several years ago and it made a huge difference, and I mean immediately (my energy floor is so low that even a small boost on that first day felt obvious). NAD is in every cell in your body and helps energy flow through your mitochondria. There are several ways to make more NAD. Here, the important thing to know is that NR (a molecule made naturally from Vitamin B3) works in those pathways. NR made from your diet (or the supplement, hopefully) is taken up by your cells and converted first into NMN (another supplement option), and then into NAD. That’s pretty much the story.Besides NR this also concludes TMG. You can think of TMG as insurance to support the NAD pathway when it’s being supplemented. TMG comes naturally from green veggies and helps with a biochemical process called methylation. When the NAD pathway is supplemented — long story short — your cells end up having to do alot more of that methylation, so having TMG around will support the extra methylation activity. I hope that makes sense, but anyway, that’s why there’s TMG.ProHealth is an excellent, highly trusted brand. It third-party tests its supplements THREE times and POSTS THE RESULTS, probably because they’ve got nothing to be afraid of: they’re all made in the US, in an FDA-registered GMP facility, and clinically studied. This came double safety-sealed and arrived with just under a year of expiration left (hmm, usually you get more than that, but maybe because this is Vine testing?). 500mg is the standard NR dose, so that’s good. This NR is NR-malate, which is a newer form, thought to be more shelf stable and easier to absorb (it used to be all NR-Chloride, which is what some companies still make so you might want to compare for yourself). While I can’t tell you how you’ll feel in the long-term on this, I can say it’s a quality product and give it the 5 stars it deserves.Lastly, from experience, my rec is to try several of the ways to supplement the NAD pathway (ProHealth makes many) to make sure you’re using whichever feels best to you. For instance, after playing around with NMN supplements, I learned supplementing NMN makes me feel a slightly “jittery” energy in comparison to the energy I get from NR (more normal). ProHealth offers a 100 day 100% guarantee and a free consultation with one of their experts to help you choose, so there’s no sense in not trying.