- Supports Normal Histamine Levels - A synergistic blend of nutrients that provides natural support to help balance the immune response.*
- Quercetin & Bromelain - Quercetin may promote normal histamine metabolism. Bromelain promotes normal mucus clearance and may help to lower occasional complaints upon exposure to common environmental triggers.*
- Nettles & Bicarbonate Salts - Nettle leaf and vitamin C have been historically used to support immune balance. Bicarbonate salts are included for their role in maintaining normal histamine metabolism, while luteolin helps maintain overall immune function.*
- Vegan & Non-GMO - Manufactured in a GMP registered facility in the USA from US and globally sourced ingredients. Vegan and vegetarian-friendly, made without Gluten, GMOs, Dairy or Soy.
- Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

MicheleK –
Best allergy remedy I’ve used
I am new to the world of using natural remedies instead of medicines but HistaEze has been amazing for me. While everyone around me had been sneezing, stuffy, has itchy eyes, etc. I have been symptom free for the first time. I am also allergic to animals but have not had issues there either. There is also no “medicine head” feeling anymore. At one point I broke out with eczema over almost my entire body. Nothing I took that was traditional medicine helped. A few doses of HistaEze and itching and burning started to ease. Soon enough it was completely gone.
Martin F. Melhus –
Best relief for moderate allergies
This stuff works great. It stops my moderate allergies very effectively, and has no side effects I can detect. When my allergies are at their worst, in the fall, it still helps a lot but isn’t enough to completely control them, so I supplement with nasal sprays, saline rinses (neti pot), and OTC allergy medicines.No idea how or why it works, but when I take it, 340 days a year I don’t even think about allergies or side effects. By far the best thing I’ve found for controlling allergies.
Doc List –
Best product of its kind that I have found
I’ve tried all sorts of allergy products. I’m slightly allergic to the whole world so I have spent much of my life slightly congested, slightly uncomfortable, with a slightly congested or drippy nose. Not terrible, but noticeable. I discovered this product at my chiropractor’s office and decided to give it a try. It’s not the cheapest by quite a margin. What I found is that my symptoms are significantly reduced, I have no side effects, and I’m more comfortable all the time. When I’ve run out, from time to time, I can almost immediately detect the difference. This has become a standard part of my daily regimen, I just wish it weren’t so expensive.
Popcorn –
Amazing product for me! Really is life-changing!
I’ve had the worst headaches for my whole adult life and the last two years, they’ve been almost unbearable. I get cluster, sinus, migraine, allergy and tension headaches. It’s no picnic. I’ve lost so much sleep and tried everything, I thought. A natural healing nurse practitioner told me about them and I thought, what could I lose? This is my second bottle on the second month and I have only felt like I MAY get a headache two or three times in all of that time. I am completely better! Thank you for this amazing product! I’m healed!
Cristina Bowen –
Horrible customer service experiences & products didn’t work
My dr suggested this brand and a specific product… I tried the supplement (it wasn’t as good as the product I was using before it but that one was out-of-stock)… Then I couldn’t get Design for Health’s product from Amazon (they were out) and it took over a month to get the product from my doctor’s office. When I restarted the supplement it didn’t work at all.When I called Designs for Health about the fact Amazon was out of their product they said they’d have to wait til Amazon restocked. I was like you aren’t going to check-in with Amazon? They said no. Amazon said it was Designs for Health’s fault.Designs for Health made no effort to help me get access to the supplement I needed. When my doctor wasn’t on their list of providers instead of seeing if he wanted to be on it – they wanted me to change providers!!! How lazy can they be?I called again to give them an update on how their product stopped working because I was off it for so long and how they have lost a customer. Again, such poor customer service. They have no business sense. I can only imagine their corporate environment with these experiences.Don’t bother trying the products… I’ve tried two and they didn’t help. They are definitely not worth the stress & incompetence I faced trying to get the products.
karenq –
Histamine intolerance assist
Along with other OTC antihistamines this formulation works well for my histamine intolerance though it is quite pricey if taken in the quantity suggested which is 4 capsules per day. Luckily I don’t need that many and find if I take more than two I have an inward chill.I usually don’t have any issues w/ Amazon deliveries but w/ this particular order the Amazon truck driver left the package at the end of my driveway(practically on the road!) instead of bringing it to the porch. Luckily I received an email from Amazon w/ an image so I was alerted and could then search the property.
Ben –
My PT recommended this!
I had bad histamine reactions that had no real pattern to them. (I have a lot of issues with my neck and nervous system.) I took these for about 3 months and slowly weaned off of them. No more bad histamine reactions! Very good for a reset to your immune system.
Amazon Customer –
Works fast
Helps with my histamine issues. Works fast. I really like it.